Uremic Symptoms - Chronic Kidney Disease Stage 5 - eGFR less than 15 ml/min

When a person reaches end-stage renal disease (ESRD), both kidneys have stopped or almost stopped doing their jobs. Patients start developing symptoms when their eGFR is Below 15 ml/min ( Stage 5 Chronic Kidney Disease) .

The body fills up with extra fluid and wastes that would normally be filtered out. This is called uremia. If you learn the signs and symptoms of uremia, you’ll be better able to watch for them and alert your doctor.

Signs Of Uremia

Head – headaches, fatigue, and fuzzy thinking can be caused by uremia.
Mouth – food may taste bad or like metal, causing a loss of appetite.
Lungs – shortness of breath can be caused by a build-up of fluid in the lungs or by anemia.
Stomach – loss of appetite, nausea, and vomiting can occur if uremia is very severe.
Bladder – less (or no) urine may be produced. Some people still make urine, but it is mostly fluid - the wastes are not removed.
Nerves- Tremors, excessive sleeping
Hands – swelling can be caused by fluid build-up.
Feet – swelling can be caused by fluid build-up.
Skin – build-up of uremic wastes can cause severe itching.
Blood vessels – high blood pressure can occur because the failing kidneys no longer keep blood pressure at normal levels.